New study from Stockholm University and Karolinska Institutet displays that viruses in the biological fluids communicate with proteins of their host which leads to a proteins layer on the viral surface. This layer of proteins makes the virus more dangerous and makes easy the making of plaques properties of neurodegenerative disorders such as Alzheimer’s disease.
Are viruses alive or dead? Well… both. Viruses can only be created within living cells and they exploit the cellular mechanism of their host to their advantage. On the other hand, before making an entry in a host cell, viruses are just tiny particles, very analogous to manmade nanoparticles employed for therapy and diagnosis in medical applications. Researchers from Stockholm University and Karolinska Institutet have discovered that nanoparticles and viruses share one more essential property; they both get covered by a coating of proteins when they meet with their host’s biological fluids before they discover their target cell. This layer of proteins on the surface significantly manipulates their biological activity.
“Envision a tennis ball dropping into a bowl of cereals and milk. The ball is immediately covered by the gluey particles in the blow and they stay on the ball when you remove the ball out of the bowl. The same thing takes place when a virus communicates with lung or blood fluids that have numerous proteins. Many of these proteins instantly stick to the viral surface making a supposed protein corona,” Stockholm University’ Kariem Ezzat claimed to the media.
On a related note, dengue, also dubbed as dengue fever, is a viral disease given by the genus Aedes’ mosquitoes to humans. The occurrence of dengue is presently elevating radically, and it is now one of the diseases claimed to be surfacing up again. In Bangladesh, in the 1960s sporadic incidence were reported and a huge outbreak took place in 2000, with clinical instances reported yearly since then.